Inside SPRIND’s jury for Continuous Hormone Monitoring
Events Giulia Paggiola Events Giulia Paggiola

Inside SPRIND’s jury for Continuous Hormone Monitoring

From wearable bioelectronics to metabolic research to decades of clinical obstetrics — the jury for SPRIND's Continuous Hormone Monitoring Challenge brings together an unusually wide range of expertise. Here's who's in the room, and where Edge Compliance fits in to assess regulatory strategy.

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On "human in the loop" and automation bias
Opinion Giulia Paggiola Opinion Giulia Paggiola

On "human in the loop" and automation bias

A widely circulated exchange about AI and military targeting raises a question every QARA professional should sit with: does "a human makes the final decision" really resolve anything when review time is a glance? Plus what's missing from the EU AI Act's high-risk categories, and new Commission guidance for health AI.

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Top nominated!
Opinion Giulia Paggiola Opinion Giulia Paggiola

Top nominated!

A year of weekly LinkedIn posts on medtech regulation just earned a "top new voice" nod — and it's got me thinking about why manual, deliberately human writing still cuts through an increasingly AI-saturated feed. Plus my personal top-10 list of medtech voices worth following.

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Notes from Scarlet's digital health summit
Events Giulia Paggiola Events Giulia Paggiola

Notes from Scarlet's digital health summit

A day of genuinely open debate on digital health regulation: why the risk of not approving a solution deserves as much weight as the risk of approving one, what duty of care looks like at consumer-platform scale, and whether continuous deployment can ever fit inside traditional regulatory review.

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LLMs for health advice get separate treatment
Analysis Giulia Paggiola Analysis Giulia Paggiola

LLMs for health advice get separate treatment

Over 5% of all ChatGPT messages are health-related, and 40 million people ask it health questions daily — yet it isn't regulated as a medical device, while purpose-built health apps are. Part 1 of a three-part series on why AI regulation creates disparity, not just innovation.

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New Zealand: an under-explored SaMD frontier
Analysis Giulia Paggiola Analysis Giulia Paggiola

New Zealand: an under-explored SaMD frontier

New Zealand still regulates medical devices under a 1981 law never built for software — meaning most low-risk SaMD can reach market today with a simple, free notification and no pre-market review. Here's what that window looks like, how long it lasts, and why it pairs naturally with Australia.

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Australia as a first GTM for SaMD
Analysis Giulia Paggiola Analysis Giulia Paggiola

Australia as a first GTM for SaMD

Australia's TGA released fresh SaMD guidance in early 2026 — and it's a case study in what good regulation can look like: plain-language self-assessment, genuine low-risk carve-outs, and enforcement that actually backs the framework. Here's why it's often my recommended first market for digital health founders.

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One year in, and incorporating
Giulia Paggiola Giulia Paggiola

One year in, and incorporating

A year into full-time self-employment, I'm incorporating a Swiss GmbH to house two ventures: Edge Compliance's regulatory work for femtech startups, and Onya Health's early bet on reducing birth trauma through better labour planning. Here's what year one actually looked like, in numbers.

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The price tag on being a woman
Opinion Giulia Paggiola Opinion Giulia Paggiola

The price tag on being a woman

Menstruation costs the average person £20,359 over a lifetime — before contraception, birth, or menopause even enter the picture. Layered onto a persistent gender pay gap, this isn't a private budgeting problem. It's a structural cost that deserves the same scrutiny as any other health inequity.

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Translating your device into "regulatorese"
Analysis Giulia Paggiola Analysis Giulia Paggiola

Translating your device into "regulatorese"

Struggling to translate your device into "regulatorese"? Our collaborator Erica Perrier of Evidentia Consulting built a free AI tool around three deceptively simple questions — what does it do, who is it for, how does it work. I tested it on fertility devices: here's what it nailed, what it missed, and why those three questions matter more than they sound.

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Optimised for the optimised
Opinion Giulia Paggiola Opinion Giulia Paggiola

Optimised for the optimised

Health tech has never had more data or more capital — yet population health outcomes haven't moved. This article looks at why the wellness-to-medical staged strategy is harder than it looks, and what regulation, funding data, and public health theory tell us about who we're actually building for.

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One day, we won't need to call it "women's health"
Events Giulia Paggiola Events Giulia Paggiola

One day, we won't need to call it "women's health"

A decade ago, "green chemistry" was a hard sell — now it's just how chemistry gets done. Drawing on that shift, here's why women's health is on the same trajectory, and what regulation, funding data, and momentum tell us about how fast it could get there. Reflection from our attendance to Women’s Health Horizons conference in London.

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The risk in having too many risks…
Analysis Giulia Paggiola Analysis Giulia Paggiola

The risk in having too many risks…

Confusing failure modes for risks is one of the most common structural mistakes in medical device risk analysis — and one of the most costly to fix later. This article explains the difference between hazards, hazardous situations, and harm under ISO 14971, why a bloated risk analysis undermines your whole risk management process, and how one simple syntax rule can help you build a cleaner, more actionable document from the start.

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The next strategic frontiers of medtech
Analysis Giulia Paggiola Analysis Giulia Paggiola

The next strategic frontiers of medtech

Where should medtech and femtech companies focus their international expansion efforts after establishing EU and US market presence? This article analyses eight high-potential markets across four global regions — Anglosphere, East Asia, MENA, and Latin America — ranked against three strategic criteria: ROI and medtech infrastructure, femtech readiness, and regulatory alignment with international harmonisation frameworks including MDSAP and CE Mark mutual recognition agreements. Whether you are mapping your next regulatory strategy or building a market entry roadmap, this evidence-based analysis offers a practical starting point — with an honest look at what the data says and where gut instinct still has a role to play.

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